Lions designations
OL Christian Mahogany (hip) is out. He did not practice Monday, Tuesday or Wednesday.
T Blake Miller (knee) is out. He did not practice Monday, Tuesday or Wednesday.
CB D.J. Reed (foot) is questionable. He was limited Tuesday and Wednesday.
DB Christian Izien (groin) is expected to play. He practiced in full Monday, Tuesday and Wednesday.
OL Juice Scruggs (knee) is expected to play. He was limited Monday and Tuesday and practiced in full Wednesday.
Bills designations
S Cole Bishop (knee/groin) is questionable. He practiced in full Monday and was limited Tuesday and Wednesday.
RB Ty Johnson (hamstring) is questionable. He was limited Monday, Tuesday and Wednesday.
DL T.J. Sanders (knee/illness) is questionable. He was limited Monday, did not practice Tuesday and was limited Wednesday.
ILB Terrel Bernard (calf) is expected to play. He was limited Monday, Tuesday and Wednesday.
OLB Bradley Chubb (thumb) is expected to play. He practiced in full Monday and Tuesday.
DB Jordan Hancock (quad) is expected to play. He practiced in full Monday, Tuesday and Wednesday.
Long-term updates
These Lions are on IR, PUP, or NFI. This is the progress list, not this week’s game-status report.
Brian Branch (PUP). Achilles. Latest: Opened the season on the reserve list. Campbell pointed to an early October game path. Return: first eligible in Week 5.
Kerby Joseph (PUP). Knee. Latest: Opened the season on the reserve list. Return: first eligible in Week 5.
Giovanni Manu (NFI). Knee. Latest: Opened the season on the reserve list. Campbell gave a 12-14 week window. Return: first eligible after Week 4.
Cade Mays (IR). Wrist. Latest: Opened the season on the reserve list. Return: first eligible in Week 5.
Damone Clark (IR). Undisclosed. Latest: Placed on season-ending IR. Return: season-ending.
Isiah Pacheco (IR). Back. Latest: Moved to IR on Sept. 1. Return: first eligible in Week 13.
Kendrick Law (IR). ACL. Latest: Torn ACL in OTAs. Return: will miss the rest of his debut season.
Payton Turner (IR). Back. Latest: Placed on season-ending IR. Return: season-ending.
As of September 16, 2026.
