Updated September 18, 2026
This is the Week 2 Wednesday game-status report for the Detroit Lions against the Buffalo Bills at Highmark Stadium on Thursday at 8:15 p.m. ET. The Lions list 2 Out and one Questionable.
Lions designations
OL Christian Mahogany is Out with a hip injury. He did not practice Monday, Tuesday, or Wednesday.
T Blake Miller is Out with a knee injury. He did not practice Monday, Tuesday, or Wednesday.
CB D.J. Reed is Questionable with a foot injury. He was limited Tuesday and Wednesday.
DB Christian Izien and OL Juice Scruggs are on the report with no game-status designation and are expected to play. Izien (groin) was a full participant Monday through Wednesday. Scruggs (knee) was limited Monday and Tuesday and a full participant Wednesday.
Bills designations
Buffalo lists nobody Out or Doubtful.
S Cole Bishop is Questionable with a knee/groin injury. He was a full participant Monday and limited Tuesday and Wednesday.
RB Ty Johnson is Questionable with a hamstring injury. He was limited Monday through Wednesday.
DL T.J. Sanders is Questionable with a knee/illness. He was limited Monday, did not practice Tuesday, and was limited Wednesday.
ILB Terrel Bernard, OLB Bradley Chubb, and DB Jordan Hancock are on the report with no game-status designation and are expected to play. Bernard (calf) was limited Monday through Wednesday. Chubb (thumb) was a full participant Monday and Tuesday. Hancock (quad) was a full participant Monday through Wednesday.
Long-term updates
These Lions are on IR, PUP, or NFI. This is the progress list, not this week’s game-status report.
Brian Branch (PUP). Achilles. Latest: Opened the season on the reserve list. Campbell pointed to an early October game path. Return: first eligible in Week 5.
Kerby Joseph (PUP). Knee. Latest: Opened the season on the reserve list. Return: first eligible in Week 5.
Giovanni Manu (NFI). Knee. Latest: Opened the season on the reserve list. Campbell gave a 12-14 week window. Return: first eligible after Week 4.
Cade Mays (IR). Wrist. Latest: Opened the season on the reserve list. Return: first eligible in Week 5.
Damone Clark (IR). Undisclosed. Latest: Placed on season-ending IR. Return: season-ending.
Isiah Pacheco (IR). Back. Latest: Moved to IR on Sept. 1. Return: first eligible in Week 13.
Kendrick Law (IR). ACL. Latest: Torn ACL in OTAs. Return: will miss the rest of his debut season.
Payton Turner (IR). Back. Latest: Placed on season-ending IR. Return: season-ending.
As of September 18, 2026.
