The Detroit Lions play at the Buffalo Bills at Highmark Stadium in week 2 action on Thursday, September 17, 2026. Kickoff is set for 8:15 PM ET.

Dan Campbell has a four-day turnaround after overtime, and Detroit flies into Highmark Stadium on Thursday night. The live question is the secondary. Brian Branch and Kerby Joseph are still out, and New Orleans just threw for more than 400 yards in Week 1. Jared Goff has to handle Buffalo’s rush on a short week while Jahmyr Gibbs carries a thin backfield with Isiah Pacheco on injured reserve. Check the injury report for who is actually available.

Lions vs. Bills: Date, Time and TV

Game: Detroit Lions at Buffalo Bills
Date: Thursday, September 17, 2026
Kickoff: 8:15 PM ET
Location: Highmark Stadium, Orchard Park, NY
TV: Amazon Prime Video

The game airs on Amazon Prime Video.

How to Stream Lions vs. Bills

In the Lions local market, watch on Amazon Prime Video. That is the living-room path. The club still lists a Safari-only mobile web stream on DetroitLions.com for in-market phones. NFL+ can stream local and primetime games on a phone or tablet. DetroitLions.com is not a TV substitute.

Out-of-market fans in the United States watch on NFL Sunday Ticket on YouTube and YouTube TV. Sunday Ticket covers Sunday afternoon games that are not on your local CBS or FOX broadcast. It does not replace national windows.

Outside the United States: NFL Game Pass International on DAZN carries the games outside the United States and China. Rights vary by country.

Radio

Listen on the Lions Radio Network with Dan Miller and Lomas Brown on the call.

FAQ

What channel is the Lions vs. Bills game on?

Amazon Prime Video

What time do the Lions play Bills?

8:15 PM ET on Thursday, September 17, 2026

How can I stream the game if I am out of market?

NFL Sunday Ticket on YouTube and YouTube TV

How can I listen on the radio?

Lions Radio Network — Dan Miller and Lomas Brown